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Developing a warning system to predict emergence of new infectious diseases

The director of the Center for the Ecology of Infectious Diseases at UGA is working to devise an early warning system for diseases which could save lives and allow public health resources to be used more efficiently and effectively.

John Drake is a UGA Distinguished Research Professor in UGA’s Odum School of Ecology. He recently delivered a presentation at TEDxUGA titled, “The Tipping Point: What Jenga Can Teach Us About Epidemics.”

Drake says that constructing a system to detect diseases outbreaks before they reach an epidemic is a “tricky scientific puzzle.” What makes it challenging is figuring out which factors will be able to sound the alarm.

Read more about John Drake and his work by checking out the original article on UGA Today.

 

BHSI Faculty member named Georgia Athletic Association Professor in Engineering

William Kisaalita, PhD, teaches undergraduate and graduate level course work within the University of Georgia’s College of Engineering. His current research encompasses tissue engineering with an emphasis on cell-based biosensors that is applicable to drug discovery. Dr. Kisaalita has also worked on developing technology for low-resource environments. He has actively given UGA students the tools they need in order to solve real-world problems and has inspired many in the field of engineering.

Read the full article on UGA Today

Study finds two behaviors linked to high school dropout rates

A study conducted by a BHSI faculty member sheds light on how aggression and weak study skills contribute to the national high school dropout right.

Pamela Orpinas is a BHSI member and a professor of health promotion and behavior at UGA’s College of Public Health.

The study found that students dropping out have complex behavioral and academic problems, she said. The key to helping a student stay in school is spotting the signs and behaviors that put students at risk of dropping out earlier in their academic careers.

Read more here.

Read the original research article.

BHSI faculty member has developed a gene that improves biofuel synthesis from plants

Debra Mohnen in greenhouse with young Populus deltoides plants. Photo by Paul Efland.

Debra Mohnen, professor of biochemistry and molecular biology in the Franklin College of Arts and Sciences and member of UGA’s Complex Carbohydrate Research Center, along with her
research team have downplayed the role of gene GAUT4 in order to lower the internal levels of pectin in plant cell walls. The result is a plant that can be broken down into simple sugars that can then be converted into biofuels. This research was conducted in collaboration with the Department of Energy’s BioEnergy Science Center, Oak Ridge National Laboratory, University of Tennessee, ArborGen, and the National Renewable Energy Laboratory.

Read more here.

Read the full research article.

Infection-resistant coating for medical devices in development


Hitesh Handa, assistant professor in the College of Engineering, has been working to prevent infection in medical devices such as central lines and catheters. These infections affect thousands of people each year and result in prolonged hospital visits for patients. Handa has created a nitric oxide-based coating for these devices; nitric oxide is naturally used in our bodies to keep blood flowing and prevent infection. The human body will recognize catheters and various tubes as foreign invaders and clot blood around them. Aside from blood clots, a thick layer of biofilm will also form over the objects due to the attraction of microorganisms. The nitric oxide coating will allow for the reduction in clotting and the prevention of biofilm formation.

Read more about Hitesh Handa’s research here on Great Commitments.

Steven Stice named National Academy of Inventors Fellow

Steven Stice, BHSI Faculty member and director of the UGA Regenerative Bioscience Center, has joined an elite group of 912 innovators hailing from more than 250 prestigious research universities and governmental and nonprofit research institutions by becoming a National Academy of Inventors (NAI) Fellow.

NAI Fellow status is a professional distinction awarded to academic inventors and innovators who create or facilitate outstanding inventions that have had a tangible impact on the quality of life, economic development, and welfare of society.

Stice has led industry and academic research teams in the field of pluripotent stem cell research for over 25 years. At UGA his pioneering work in developmental biology and genetics has helped advance human and animal medicine.

Find out more about Steven Stice’s outstanding achievement and more about his work by reading the full article on UGA Today.

 

Focus on Faculty: Claire de La Serre

BHSI member Claire de La Serre is eager to discuss her research relating to isolating the triggers of overeating and learning about diet-driven abnormal communication between the gut and the brain. Serre is also an asset to her students as far as keeping them up-to-date on the latest research findings in foods and nutrition, in fact, she was herself once a PhD student in nutrition at the University of California; she then went on to complete her postdoctoral fellowship at John Hopkins School of Medicine in Baltimore. By making it a priority to stay-up-to-date with the latest research findings in scientific literature, Serre encourages her students to carefully analyze research papers themselves and offer up their own interpretations of data.

Find out more about Serre and her research on the gut and the brain by reading the full article here.

Brand-new Drug Discovery Core lab hopes to develop treatments of leading diseases

The Drug Discovery Core (DDC) laboratory is a brand-new, campus-wide collaborative facility that is designed to hasten the development of therapeutic drugs for a number of major diseases.

The DDC is a result of an initiative that started with a survey distributed to UGA researchers in 2016 which identified chemical screening and toxicity profiling as the most critical needs for enhancing drug discovery research at UGA. The DDC will work to address those needs for faculty who have already been working in infectious disease, regenerative medicine, cancer biology, and other human health-focused disciplines.

The DDC’s creating was initiated largely by two BHSI faculty members, Shelley Hooks, who is the interim director of the center of Drug Discovery and associate professor of pharmaceutical and biomedical science, and Brian Cummings, who is the director of the Interdisciplinary Toxicology Program and professor in the pharmaceutical and biomedical sciences department.

Find out more exciting information about the development of this initiative and its objectives by reading the full article at UGA Today.

Focus on Faculty: Andrew Park

BHSI’s very own Andrew Park talks about his experience in infectious disease research across UGA’s campus:

Find out about his parasite research is helping develop new ideas on how to manage antibiotic resistance and what his findings related to the Ebola crisis in west Africa. Read the full article here.

Feature: GRA Scholars at UGA commited to solving world’s grand challenges

The Georgia Research Alliance, a non-profit organization, has partnered with research universities since 1990 to provide world-class scientists who foster “science and technology-based development.” Many of these scholars here at UGA have enhanced the university’s research capabilities and impact.

UGA has recruited five GRA Eminent Scholars since 2015 which has led to a staggering 33 percent cumulative increase in research expenditures during the following period. These GRA program scientists bring benefits not only to the industries in which they research, but also students at UGA. Labs of GRA Eminent Scholars create high-level learning environment to help prepare them to become next-generation leaders in science.

Among these five scholars are C.J. Tsai, a GRA Eminent Scholar in Molecular Biology; Scott Jackson, a GRA Eminent Scholar in Plant Functional Genomics; Stephen Dalton, a GRA Eminent Scholar in Molecular Biology; Dennis Kyle, a GRA Eminent Scholar in Antiparasitic Drug Discovery; and Karen Norris, a GRA Eminent Scholar in Immunology and Translational Biomedical Research.

You can discover even more GRA Eminent Scholars and their research ambitions by reading the full article here.

Focus on Faculty: John Maurer

BHSI population health professor John Maurer opens up about his experience in population science in a recent “Focus on Faculty” article.

Find out about his research, his “Zombie Plague” First-Year Odyssey course and more by checking out the full article on UGA Today.

Discovery finds a drug that can be given orally for a tropical disease

Researchers at the University of Georgia, including Dr. Kojo Mensa-Wilmot, chair of the Division of Basic & Translational Biomedical Sciences within the Biomedical

and Health Sciences Institute, are working to find the fastest way possible to treat and cure human African trypanosomiasis, long referred to as sleeping sickness. By working to improve chemical entities already tested in human clinical trials, they hope to have a faster route to field studies to treat the disease using drugs that can be administered orally to patients.

The study, “Discovery of Carbazole-Derived Lead Drug for Human African Trypanosomiasis,” was published in Scientific Reports on August 26, 2016.

For more information, go to the following link: UGA Researchers Discover a Drug for a Tropical Disease.

 

Video Presentation – Civil War Historian Stephen Berry

Dr. Stephen Berry presented “CSI Dixie: Medical Science and Death Investigation in the Nineteenth Century South”” on October 7, 2015 as part of the #Throwback Therapies: History of Medical Science lecture series.

Here is the video of his presentation: BHSI – YouTube

Dr. Berry is Gregory Professor of the Civil War Era and co-founder of the Center for Virtual History at the University of Georgia. The author or editor of six books on America in the mid-nineteenth century, he also edits the UnCivil Wars series at the University of Georgia Press. A recent “Digital Innovation Fellow” of the American Council of Learned Societies, Berry also directs DigiLab, an innovation and instruction hub for the digital humanities and arts on the third floor of Main Library.

 

#Throwback Therapies is an interdisciplinary seminar series designed to entertain and enlighten any audience with interests in the origins of modern health sciences. This series is sponsored by the Biomedical & Health Sciences Institute, the Willson Center for Humanities and Arts, Department of ClassicsDepartment of History, and the Medical Partnership.

 

 

One Health Fall Seminar: Dr. Liz Kramer

Dr. Kramer presents “Sustainable Food System Initiative: Feeding the World without Eating the World “ on October 14, 2015 at 1:00pm in the Coverdell Center, Room 175 (Reception to follow).

Dr. Liz Kramer is the founding director of UGA’s Natural Resources Spatial Analysis (NARSAL) Laboratory in the College of Agricultural and Environmental Sciences and is a Public Service faculty member in the Department of Agricultural and Applied Economics. For almost 20 years NARSAL has been involve in conducting research, training and outreach in the application of geospatial technology to natural resource management and planning. Recently, Liz has added a new challenge in leading the Sustainable Food Systems Initiative (SFSI) at UGA. SFSI creates a physical and intellectual space for using a systems approach in 1) conducting interdisciplinary data-driven research that addresses interactions at multiple scales between food systems, the environment, and human health; 2) engaging students in interdisciplinary, experiential education; and 3) providing life-long educational opportunities to consumers and the people that support the food system.

Liz’s recent research involves understanding temporal and spatial dynamics of landscapes in providing an array of ecosystem services. She has a diverse portfolio of interdisciplinary research activities, which include projects in agricultural, urban, and natural systems in areas such as stormwater management, coastal resiliency to climate change, wetland mitigation and restoration, biodiversity management, and enhancing the role of beneficial insects in agricultural systems. She holds a BS in Forest Management from Michigan State University, a Master in Forest Science from Yale School of Forestry and Environmental Studies and a PhD in Ecology from University of Georgia.

Sponsored by: University of Georgia Biomedical and Health Sciences Institute

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